(Not in any particular order after 2):
1) Metal Gear Solid 4: Guns of the Patriots
2) The Legend of Zelda: Windwaker
3) Halo: Reach
4) Final Fantasy X
5) Doom 3
Although it's more of a set of games, I also really liked all the Disney Capcom scrollers of the NES era (Darkwing Duck, Ducktales, Chip 'n Dale).