One thing I've noticed is that many independent developers don't always reply to inquiries, especially if it looks like you may charge a fee. It's through looking into doing music for games I found this site.
One thing I will say is that I don't mind doing something for little or no money, so long as I don't feel to be taken advantage of. For people like myself with an interest and background in music, it's something that could be a step towards something bigger. Possibly helping the developer get noticed, possibly the music, possibly (And ideally) both.
Getting into the likes of a Sony owned house is unlikely as they have a wealth of artists they can use (Note the early Psycnosis games on the Playstation one), so independents and small software houses would be the way to get started.
Even so, easier said than done on occasion.